Description

Benzoylleucyl-Alanyl-Arginine-α-Naphthylester is a synthetic peptide derivative designed as a chromogenic substrate for enzymatic assays. This compound is valued for its specificity in biochemical research and diagnostic applications, enabling precise measurement of protease activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for enzyme kinetics studies and high-throughput screening.

Application

• Protease Activity Assays: Serves as a specific chromogenic substrate for the detection and quantification of trypsin-like serine protease activity.
• Biochemical Research: Used in enzyme kinetics studies to determine kinetic parameters (Km, Vmax) and inhibition constants (Ki).
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for clinical analysis of blood coagulation and fibrinolysis pathways.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors as potential drug candidates.
• Quality Control in Bioprocessing: Monitors protease activity during the purification and production of biopharmaceuticals like monoclonal antibodies.

Basic Information

Item	Detail
Product Name	Benzoylleucyl-Alanyl-Arginine-α-Naphthylester
CAS No.	81484-15-3
Molecular Formula	C31H41N7O5
Molecular Weight	591.71 g/mol
Synonyms	Bz-Leu-Ala-Arg-2-NA; Bz-Leu-Ala-Arg-βNA; Benzoyl-L-leucyl-L-alanyl-L-arginine 4-nitroanilide acetate salt (related); Bz-L-A-R-2NA; Chromogenic Substrate S-2765 (related to similar structures); Trypsin Chromogenic Substrate; Protease Substrate 81484-15-3; Nα-Benzoyl-L-leucyl-L-alanyl-L-arginine 2-naphthyl ester
EINECS	Contact for details

Quality Control

Our Benzoylleucyl-Alanyl-Arginine-α-Naphthylester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.