Description

(82)-n-[[[3-(Dimethylamino)Propyl]Amino]Carbonyl]-n-Ethyl-6-(2-Propen-1-Yl)-Ergoline-8-Carboxamide is a complex ergoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules targeting neurological and cardiovascular pathways. It is primarily required by R&D laboratories, analytical service providers, and pharmaceutical manufacturers engaged in the development of specialized therapeutics. The product is supplied with a focus on high purity and batch-to-batch consistency to ensure reliable research outcomes.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key synthetic intermediate or building block in the discovery of new drug candidates, particularly those based on ergot alkaloid scaffolds.
• Reference Standard for Analytical Testing: Used as a certified reference material (CRM) in HPLC, LC-MS, and NMR for method development, validation, and quality control of related substances.
• Biochemical Studies: Employed in in vitro and in vivo studies to investigate receptor binding affinity, pharmacological activity, and metabolic pathways associated with ergoline compounds.
• Process Chemistry & Scale-Up: Acts as a starting material or intermediate for process optimization and pilot-scale synthesis in a GMP or non-GMP environment.
• Academic Research: Utilized in university and institutional labs for fundamental chemical and pharmacological research on complex heterocyclic systems.
• Custom Synthesis & Contract Manufacturing: Provided as a substrate for the custom synthesis of more complex, target-specific molecules for client projects.

Basic Information

Item	Detail
Product Name	(82)-n-[[[3-(Dimethylamino)Propyl]Amino]Carbonyl]-n-Ethyl-6-(2-Propen-1-Yl)-Ergoline-8-Carboxamide
CAS No.	81409-91-8
Molecular Formula	C25H35N5O2
Molecular Weight	437.58 g/mol
Synonyms	6-Allyl-8β-[[N-ethyl-N-[[3-(dimethylamino)propyl]carbamoyl]carbamoyl]]ergoline; 8β-[[N-Ethyl-N-[[3-(dimethylamino)propyl]carbamoyl]carbamoyl]]-6-allylergoline; 6-(2-Propen-1-yl)-8β-carboxy-N-ethyl-N′-[3-(dimethylamino)propyl]ergolamide; Cabergoline Impurity; Cabergoline Related Compound; Ergoline-8-carboxamide derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (82)-n-[[[3-(Dimethylamino)Propyl]Amino]Carbonyl]-n-Ethyl-6-(2-Propen-1-Yl)-Ergoline-8-Carboxamide is produced and controlled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support development projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, well-ventilated area. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.