Description

Euk 134 is a synthetic, cell-permeable superoxide dismutase/catalase mimetic and a potent lipophilic antioxidant. This compound is scientifically significant for its ability to protect biological systems from oxidative stress by catalytically scavenging reactive oxygen species (ROS). It is a critical material for researchers and formulators in the pharmaceutical, nutraceutical, and advanced cosmetic industries, particularly for applications in anti-aging, neuroprotection, and mitochondrial health studies.

Application

• Pharmaceutical Research & Development: Used as an active pharmaceutical ingredient (API) or intermediate in preclinical studies targeting oxidative stress-related diseases, including neurodegenerative disorders, ischemia-reperfusion injury, and inflammatory conditions.
• Cosmeceutical Formulations: Incorporated into high-performance skincare products such as serums, creams, and lotions for its potent anti-aging and photoprotective properties, helping to neutralize free radicals generated by UV exposure.
• Nutraceutical & Dietary Supplements: Serves as a key ingredient in advanced supplement formulations aimed at supporting cellular health, reducing oxidative damage, and promoting longevity.
• Biochemical Research Reagent: Employed as a standard or tool compound in laboratory studies to investigate antioxidant mechanisms, mitochondrial function, and redox biology in cell cultures and animal models.
• Industrial Antioxidant Systems: Potential application in stabilizing sensitive materials against oxidative degradation in specialized chemical processes or polymer formulations.

Basic Information

Product Name	Euk 134
CAS No.	81065-76-1
Molecular Formula	C20H32N4O4Cl2Mn
Molecular Weight	502.34 g/mol
Synonyms	EUK-134; EUK 134; EUK134; Manganese 3-methoxy N,N'-bis(salicylidene)ethylenediamine chloride; Manganese 3-methoxy salen chloride; M40403; SC-1; SOD/Catalase mimetic EUK-134; Chloro[(2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO])]-manganese; JNJ 1033
EINECS	Contact for details

Quality Control

Our Euk 134 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, heavy metal analysis, and residual solvent screening, to ensure it meets stringent specifications for research and formulation use. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Brown to dark brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.