Description

1-Naphthyl Phosphate Monosodium Salt Monohydrate is a high-purity organic phosphate ester salt widely used as a key biochemical reagent and synthetic intermediate. Its primary value lies in its role as a substrate for various phosphatases, including alkaline phosphatase, making it essential for enzymatic assays and diagnostic applications. This compound is critical for research institutions, diagnostic kit manufacturers, and pharmaceutical companies involved in biochemical research, clinical diagnostics, and fine chemical synthesis.

Application

• Enzymatic Assay Substrate: Primary substrate for colorimetric and fluorometric detection of alkaline phosphatase (ALP) activity in research and clinical diagnostics.
• Diagnostic Reagent: Key component in the manufacturing of diagnostic kits and strips for measuring ALP levels, a crucial biomarker for liver and bone disorders.
• Biochemical Research: Used in enzyme kinetics studies, inhibitor screening, and molecular biology research involving phosphate metabolism.
• Fine Chemical Synthesis: Serves as a protected phosphate intermediate or a building block in the synthesis of more complex nucleotides and pharmaceutical compounds.
• Industrial Biocatalysis: Potential application as a phosphate donor in enzymatic synthesis processes within industrial biotechnology.

Basic Information

Product Name	1-Naphthyl Phosphate Monosodium Salt Monohydrate
CAS No.	81012-89-7
Molecular Formula	C10H8NaO4P · H2O
Molecular Weight	264.13 g/mol (Monohydrate)
Synonyms	α-Naphthyl Phosphate Monosodium Salt; 1-Naphthyl Dihydrogen Phosphate Monosodium Salt; Sodium 1-Naphthyl Phosphate; Phosphoric Acid Mono(1-naphthyl) Ester Sodium Salt; ALP Substrate; 1-Naphthyl Acid Phosphate Sodium Salt; NSC 401008; 1-Naphthylphosphoric Acid Sodium Salt Monohydrate
EINECS	Contact for details

Quality Control

Our 1-Naphthyl Phosphate Monosodium Salt Monohydrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is subjected to rigorous analytical testing, including HPLC for purity and assay, IR for identification, and specific tests for moisture and related substances. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all quality parameters. Our production adheres to cGMP principles where applicable, supporting its use in regulated diagnostic and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which can affect purity and stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	5.0% - 7.5% (Theoretical for monohydrate: ~6.8%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, methanol
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.