Description

3'-Amino-3'-Deoxy-5-Fluorouridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound is valued for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based drugs. Our supply ensures high purity and consistent quality to meet the stringent demands of advanced life science applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Antiviral Drug Development: Investigated for its potential activity against viral targets due to its fluorinated uridine structure.
• Oncology Research: Explored for its cytotoxic properties and mechanism of action in cancer cell line studies.
• Prodrug Synthesis: Utilized as a core structure for developing prodrugs with improved bioavailability and targeting.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	3'-Amino-3'-Deoxy-5-Fluorouridine
CAS No.	80955-97-1
Molecular Formula	C9H11FN3O5
Molecular Weight	260.20 g/mol
Synonyms	5-Fluoro-3'-amino-2',3'-dideoxyuridine; 3'-Amino-2',3'-dideoxy-5-fluorouridine; 3'-Amino-5-fluoro-2',3'-dideoxyuridine; 5-Fluoro-3'-amino-2',3'-dideoxyuridine; 3'-Amino-3'-deoxy-5-fluorouridine; 5-Fluorouridine, 3'-amino-3'-deoxy-; 80955-97-1; 3'-Amino-5-fluorouridine, 3'-deoxy-
EINECS	Contact for details

Quality Control

Our 3'-Amino-3'-Deoxy-5-Fluorouridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.