Description

Pefachrome(R) Fxa* is a high-purity chromogenic substrate specifically designed for advanced enzymatic assays. This compound is critical for precise biochemical analysis, offering superior sensitivity and reliability in diagnostic and research applications. It is primarily utilized by manufacturers and research laboratories in the in-vitro diagnostics (IVD), pharmaceutical R&D, and life sciences sectors for detecting specific enzyme activities.

Application

• In-Vitro Diagnostic (IVD) Kits: As a key chromogenic component in clinical chemistry analyzers for measuring enzyme markers like Factor Xa and other serine proteases.
• Pharmaceutical Research: Used in high-throughput screening (HTS) assays to identify and characterize potential drug candidates targeting coagulation pathways.
• Biochemical Research: Employed in enzymatic kinetics studies to determine reaction rates, inhibition constants (Ki), and enzyme specificity.
• Quality Control in Biologics: For monitoring and quantifying residual proteolytic enzyme activity during downstream biopharmaceutical purification processes.
• Hematology Studies: Applied in research focused on blood coagulation disorders, thrombosis, and hemostasis mechanisms.

Basic Information

Product Name	Pefachrome(R) Fxa*
CAS No.	80895-10-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pefachrome FXa; Chromogenic Substrate for Factor Xa; Boc-Ile-Glu-Gly-Arg-pNA; Boc-Ile-Glu-Gly-Arg-p-Nitroanilide; FXa Chromogenic Substrate; Factor Xa Substrate; S-2765 (Competitive/Related Product); Z-D-Arg-Gly-Arg-pNA (Related Structure)
EINECS	Contact for details

Quality Control

Our Pefachrome(R) Fxa* is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for diagnostic and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may affect performance. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water
Functional Activity	Conforms to reference in Factor Xa assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.