Description

1-Tetradecanoyl-2-[cis-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phosphatidylcholine (PC) lipid, a critical building block for advanced biomembrane research and formulation. This compound matters for its defined acyl chain composition, offering superior consistency and reproducibility compared to natural extracts for sensitive applications. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors who require precise lipid components for liposome development, drug delivery systems, and membrane biophysics studies.

Application

• Liposome & Nanoparticle Formulation: A key phospholipid component for creating stable, uniform liposomes used in drug delivery and vaccine adjuvants.
• Biomembrane & Model Membrane Studies: Used to construct synthetic lipid bilayers (e.g., vesicles, supported lipid bilayers) for studying membrane protein interactions, permeability, and fusion mechanisms.
• Cell Culture & Transfection Reagents: Incorporated into lipid mixtures to enhance the efficiency of nucleic acid delivery into cells.
• Diagnostic Reagents & Assay Kits: Serves as a standard or a functional component in diagnostic kits for enzymatic assays and lipid metabolism studies.
• Cosmetic & Dermal Delivery Systems: Used in high-end cosmetic formulations for its emulsifying properties and ability to improve skin barrier function and active ingredient penetration.
• Biophysical Research: A standard for calorimetry (DSC), spectroscopy, and microscopy studies due to its defined phase transition behavior.

Basic Information

Product Name	1-Tetradecanoyl-2-[cis-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine
CAS No.	80863-06-5
Molecular Formula	C40H78NO8P
Molecular Weight	732.01 g/mol
Synonyms	PC(14:0/18:1(9Z)); 1-Myristoyl-2-oleoyl-sn-glycero-3-phosphocholine; MOPC; 14:0-18:1 PC; POPC analog (C14:0/C18:1); Phosphatidylcholine (14:0/18:1(9Z)); 1-Tetradecanoyl-2-oleoyl-sn-glycero-3-phosphocholine; (2R)-2,3-Bis[[(Z)-octadec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate
EINECS	Contact for details

Quality Control

Our synthetic phospholipids are produced under strict quality management to ensure batch-to-batch consistency and high purity, typically exceeding 99% by HPLC. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and research applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Once opened, use promptly and minimize exposure to ambient air and moisture. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Approx. -5°C to 0°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.