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2-Amino-5-[[(2R,3R,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2 -Yl]Methylamino]Pentanoic Acid CAS NO 80860-79-3
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CAS No.:80860-79-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-5-[[(2R,3R,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2 -Yl]Methylamino]Pentanoic Acid is a high-purity, nucleoside-derived amino acid compound of significant interest in advanced pharmaceutical research and development. This specialized chemical serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation nucleotide analogs and targeted biologics.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleotide analog drugs.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and polymerase function.
- Proteomics & Molecular Biology: Employed in the development of labeled probes and tools for studying nucleic acid-protein interactions.
- Precision Medicine Development: Serves as a building block for creating targeted therapeutic conjugates and antibody-drug conjugates (ADCs).
- Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and chemical biology.
- Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-Amino-5-[[(2R,3R,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2 -Yl]Methylamino]Pentanoic Acid |
| CAS No. | 80860-79-3 |
| Molecular Formula | C15H21N7O5 |
| Molecular Weight | 379.37 g/mol |
| Synonyms | N6-Methyl-2'-deoxyadenosyl-L-lysine; Lysine conjugated with 2'-Deoxyadenosine; L-Lysine, N6-(2'-deoxyadenosin-5'-yl)-; 5'-Deoxy-5'-(N6-L-lysyl)adenosine; Nucleoside-Amino Acid Conjugate; 2'-Deoxyadenosine-L-lysine conjugate; 5'-(N6-L-Lysyl)-2'-deoxyadenosine |
| EINECS | Contact for details |
Quality Control
Our 2-Amino-5-[[(2R,3R,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2 -Yl]Methylamino]Pentanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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