Description

1,3-Dioleoyl-2-(4-Pyrenylbutanoyl)Glycerol is a specialized synthetic glycerolipid derivative designed for advanced research and development applications. This compound is valued for its unique structural features, combining the properties of oleic acid and a pyrene fluorophore, which makes it an essential tool in fluorescence-based studies. It is primarily sought by researchers and product developers in the life sciences, pharmaceutical development, and advanced material science sectors. Its precise structure enables critical investigations into lipid metabolism, membrane dynamics, and as a fluorescent probe.

Application

• Fluorescent Lipid Probe: Used as a sensitive tracer for studying lipid trafficking, membrane fusion, and intracellular dynamics in cell biology research.
• Biomembrane Research: Serves as a key component in model membrane systems (e.g., liposomes, bilayers) to investigate phase behavior and lipid-protein interactions.
• Drug Delivery System Development: Incorporated into lipid-based nanoparticle formulations (LNPs, liposomes) as a traceable component to monitor delivery efficiency and biodistribution.
• Enzymology Studies: Acts as a substrate or inhibitor for enzymes involved in lipid metabolism, such as lipases and acyltransferases.
• Diagnostic Assay Development: Utilized in the design of fluorescence-based diagnostic kits and sensors for detecting specific biological activities.
• Material Science: Employed in the synthesis of functionalized materials where a fluorescent lipid anchor is required for surface modification or labeling.

Basic Information

Product Name	1,3-Dioleoyl-2-(4-Pyrenylbutanoyl)Glycerol
CAS No.	80749-89-9
Molecular Formula	C71H100O6
Molecular Weight	1049.55 g/mol
Synonyms	Pyrene-labeled triacylglycerol; 1,3-Di(cis-9-octadecenoyl)-2-[4-(1-pyrenyl)butanoyl]glycerol; 2-(4-Pyrenylbutanoyl)-1,3-dioleoylglycerol; Glycerol 1,3-dioleate 2-(4-pyrenebutyrate); TAG-Pyrene; Fluorescent triglyceride analog; Pyrene butyric acid triglyceride
EINECS	Contact for details

Quality Control

Our 1,3-Dioleoyl-2-(4-Pyrenylbutanoyl)Glycerol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with rigorous laboratory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown viscous oil or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Pyrene Content (Fluorimetry)	Conforms to theoretical
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.