Description

D(-)3-Phosphoglyceric Acid Disodium Salt is a high-purity, biologically active isomer of 3-phosphoglycerate, a critical intermediate in the glycolytic and Calvin cycles. This compound is essential for research and development in biochemistry and enzymology, offering a defined stereochemical configuration for precise metabolic studies. It is primarily utilized by biotech R&D laboratories, pharmaceutical companies developing metabolic pathway modulators, and manufacturers of diagnostic enzymes and kits.

Application

• Biochemical Research: A key substrate and intermediate for studying glycolysis, gluconeogenesis, and the Calvin cycle in plant biochemistry.
• Enzyme Assay & Characterization: Used as a specific substrate for enzymes such as phosphoglycerate kinase (PGK) and phosphoglycerate mutase in activity assays and kinetic studies.
• Diagnostic Reagent Manufacturing: Serves as a critical raw material in the formulation of diagnostic kits for clinical chemistry that measure enzyme activities or metabolic markers.
• Pharmaceutical Development: Employed in metabolic pathway research for drug discovery programs targeting diseases like cancer or metabolic disorders.
• Cell Culture & Metabolism Studies: Used in defined media or as a metabolic tracer to investigate cellular energy metabolism and flux analysis.
• Reference Standard: Acts as a high-purity chromatographic or spectroscopic standard for quality control in related bioprocesses.

Basic Information

Product Name	D(-)3-Phosphoglyceric Acid Disodium Salt
CAS No.	80731-10-8
Molecular Formula	C3H5Na2O7P
Molecular Weight	236.02 g/mol
Synonyms	D-3-Phosphoglyceric Acid Disodium Salt; (R)-3-Phosphoglyceric Acid Disodium Salt; D-(-)-3-Phosphoglycerate Disodium Salt; 3-PGA Disodium Salt; D-Glycerate 3-Phosphate Disodium Salt; PGADisodium; 3-Phospho-D-glyceric Acid Disodium Salt; 2-Hydroxy-3-(phosphonooxy)-propanoic Acid Disodium Salt
EINECS	Contact for details

Quality Control

Our D(-)3-Phosphoglyceric Acid Disodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation [α]20/D	-10.0° to -14.0° (c=1 in H2O)
pH (5% Solution)	6.0 - 8.0
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.