Description

1,3-Dihydro-6,7-Dimethoxy-3-(5,6,7,8-Tetrahydro-4-Methoxy-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Yl)Isobenzofuran-1-Ol is a complex heterocyclic organic compound belonging to the isoquinoline alkaloid family, serving as a critical advanced intermediate in pharmaceutical synthesis. Its intricate fused-ring structure makes it a valuable building block for developing novel bioactive molecules. This high-purity compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those focused on central nervous system (CNS) agents and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel alkaloid-derived pharmaceuticals.
• Neurological Research: Used in the synthesis of compounds for studying and targeting neurological receptors and pathways.
• Medicinal Chemistry R&D: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its complex stereochemistry for producing enantiomerically pure compounds.
• Biochemical Tool Compound: Acts as a probe or inhibitor in biochemical assays to investigate specific enzyme or receptor functions.

Basic Information

Product Name	1,3-Dihydro-6,7-Dimethoxy-3-(5,6,7,8-Tetrahydro-4-Methoxy-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Yl)Isobenzofuran-1-Ol
CAS No.	80666-03-1
Molecular Formula	C24H27NO7
Molecular Weight	441.48 g/mol
Synonyms	6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one (tautomer); Galanthamine intermediate; Lycoramine-type alkaloid derivative; 1-Ol isobenzofuran derivative; Narcissus alkaloid analog; 80666-03-1; 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl substituted phthalide
EINECS	Contact for details

Quality Control

Our production of 1,3-Dihydro-6,7-Dimethoxy-3-(5,6,7,8-Tetrahydro-4-Methoxy-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Yl)Isobenzofuran-1-Ol adheres to stringent quality management systems, ensuring batch-to-batch consistency for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and MS to verify chemical structure and meet the exacting standards required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.