Description

H-His-Ser-4Mβna CAS NO 80567-33-5 is a specialized synthetic peptide derivative, specifically a fluorogenic substrate designed for protease activity studies. This compound is of significant value in biochemical research and pharmaceutical development for its role in enabling precise, sensitive enzymatic assays. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in protease inhibitor screening, enzyme kinetics, and biomarker discovery.

Application

• Protease Activity Assays: As a fluorogenic substrate for the detection and quantification of specific protease enzyme activities.
• High-Throughput Screening (HTS): Used in pharmaceutical R&D for screening libraries of compounds to identify novel protease inhibitors.
• Enzyme Kinetics Studies: Essential for determining kinetic parameters (Km, Vmax) of target proteases in biochemical research.
• Diagnostic Development: A key component in the development of clinical diagnostic tests that measure protease levels as disease biomarkers.
• Cell Biology Research: Employed in studies of intracellular proteolytic pathways and signaling cascades.
• Quality Control in Biologics: Used to monitor and ensure the absence of specific protease activities in biopharmaceutical manufacturing processes.

Basic Information

Product Name	H-His-Ser-4Mβna
CAS No.	80567-33-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	H-His-Ser-4-Methoxy-β-naphthylamide; Histidyl-Seryl-4-Methoxy-2-naphthylamide; Fluorogenic Substrate for Proteases; 4-Methoxy-β-naphthylamide derivative of His-Ser dipeptide; Protease Substrate 80567-33-5; His-Ser-4MNA
EINECS	Contact for details

Quality Control

Our H-His-Ser-4Mβna is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via mass spectrometry, to ensure it meets the exacting standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 98% (on dry basis)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.