Description

N(Alpha)-(4-Toluenesulfonyl)-4-Amidinophenylalanylpiperidine is a specialized, high-purity chemical building block designed for advanced research and development. This compound is critical for medicinal chemistry applications, particularly in the synthesis of novel protease inhibitors and other biologically active molecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on drug discovery and biochemical pathway analysis.

Application

• Pharmaceutical Intermediates: Serves as a key synthetic precursor in the development of novel therapeutic agents, particularly protease inhibitors.
• Medicinal Chemistry Research: Used as a sophisticated building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme mechanisms and inhibition kinetics.
• Peptidomimetic Synthesis: Integral for constructing complex peptidomimetic scaffolds that mimic natural peptides.
• Academic & Contract Research: Supports fundamental research in organic synthesis and bioorganic chemistry at universities and CROs.

Basic Information

Product Name	N(Alpha)-(4-Toluenesulfonyl)-4-Amidinophenylalanylpiperidine
CAS No.	80456-99-1
Molecular Formula	C22H28N4O3S
Molecular Weight	428.55 g/mol
Synonyms	4-Amidino-N-α-(4-methylphenyl)sulfonyl-DL-phenylalanylpiperidine; Tosyl-4-Amidinophenylalanylpiperidine; Nα-(p-Toluenesulfonyl)-4-amidinophenylalanylpiperidine; 4-Amidino-Nα-(4-methylbenzenesulfonyl)-DL-phenylalanylpiperidine; 80456-99-1; Amidino-Phe(Pbf)-piperidine derivative; Protease Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our N(Alpha)-(4-Toluenesulfonyl)-4-Amidinophenylalanylpiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.