Description

Leurosidine N'B-Oxide is a specialized alkaloid derivative with significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies focused on oncology and other therapeutic areas requiring high-purity, structurally defined compounds. The product is supplied with full analytical characterization to ensure reliability for sensitive applications.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant for analytical methods (HPLC, LC-MS) in drug development and quality control laboratories.
• Biochemical Research: Serves as a key intermediate or tool compound in the study of alkaloid biosynthesis, structure-activity relationships (SAR), and mechanism of action.
• Oncology Research: Investigated for its potential biological activity and as a precursor in the synthesis of novel anti-cancer agent candidates.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and pharmacological studies.
• Process Chemistry: Acts as a building block in the scalable synthesis of more complex natural product derivatives for pre-clinical evaluation.

Basic Information

Product Name	Leurosidine N'B-Oxide
CAS No.	80374-74-9
Molecular Formula	C46H56N4O10
Molecular Weight	824.97 g/mol
Synonyms	Leurosidine N-oxide; Vincaleukoblastine N-oxide (Leurosidine); 3',4'-Didehydro-4'-deoxyvincaleukoblastine N-oxide; 3',4'-Anhydrovinblastine N-oxide; NSC 365798; Leurosidine Oxide; 4'-Deoxy-3',4'-didehydrovincaleukoblastine N-oxide
EINECS	Contact for details

Quality Control

Our Leurosidine N'B-Oxide is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for reference materials, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.