Description

8-Acetonyldihydronitidine is a specialized alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies focused on oncology, antimicrobial agents, and other therapeutic areas. Our supply ensures high purity and batch-to-batch consistency to meet the stringent demands of modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways of potential therapeutic alkaloids.
• Biochemical Research: Used as a reference standard in studies investigating the structure-activity relationships (SAR) of nitidine-related compounds.
• Anticancer Agent Development: Serves as a precursor or analog in the research of new chemotherapeutic candidates targeting various cancer cell lines.
• Antimicrobial Studies: Employed in research programs aimed at developing new agents against resistant bacterial and fungal strains.
• Natural Product Synthesis: A valuable synthon for the partial or total synthesis of complex natural products for pharmacological evaluation.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	8-Acetonyldihydronitidine
CAS No.	80330-39-8
Molecular Formula	C23H23NO5
Molecular Weight	393.44 g/mol
Synonyms	8-Acetonyl-5,6-dihydronitidine; Nitidine, 8-acetonyl-5,6-dihydro-; 5,6-Dihydro-8-acetonylnitidine; 2,3-Dimethoxy-12-methyl-8-(3-oxobutyl)[1,3]benzodioxolo[5,6-c]phenanthridin-13-ium; 8-(3-Oxobutyl)-5,6-dihydronitidine; Benzo[c]phenanthridine alkaloid derivative
EINECS	Contact for details

Quality Control

Every batch of 8-Acetonyldihydronitidine is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.