Description

8(R),15(S)-Dihete is a high-purity, stereochemically defined bioactive lipid mediator. This compound is of significant interest for advanced research and development due to its role in specialized biochemical pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical and life science sectors for studying inflammatory and regulatory processes. Our supply ensures consistent quality and reliable availability for critical applications.

Application

• Biochemical Research: Used as a reference standard and active compound in studies of eicosanoid signaling and lipid metabolism.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the development of novel anti-inflammatory and immunomodulatory therapeutics.
• Cell Biology Studies: Applied in vitro to investigate cellular responses, receptor interactions, and pathway modulation.
• Analytical Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quantitative analysis.
• Enzyme Substrate/Inhibitor Studies: Used to probe the activity and specificity of lipoxygenases and related enzymes.

Basic Information

Product Name	8(R),15(S)-Dihete
CAS No.	80234-67-9
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	8(R),15(S)-DiHETE; (8R,15S)-Dihydroxy-5Z,9E,11Z,13E-eicosatetraenoic Acid; 8(R),15(S)-Dihydroxyeicosatetraenoic Acid; 8,15-DiHETE; 8(R),15(S)-DiHETE; 8,15-Dihydroxy-5,9,11,13-eicosatetraenoic Acid; 8(R),15(S)-DHETE; 8,15-Leukotriene B4
EINECS	Contact for details

Quality Control

Our 8(R),15(S)-Dihete is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support research and cGMP-grade manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/UV)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.