Description

Adenosine 5'-Diphosphate-Glycero-Mannoheptose is a key biochemical intermediate involved in the biosynthesis of bacterial cell wall components, specifically the inner core region of lipopolysaccharides (LPS) in Gram-negative bacteria. Its role in the metabolic pathway makes it a critical compound for research in microbiology, glycobiology, and the development of novel antibacterial agents. This high-purity material is essential for academic and industrial researchers focusing on bacterial pathogenesis, vaccine development, and enzymatic studies related to nucleotide-sugar metabolism.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic assays to study the biosynthesis and assembly of lipopolysaccharide (LPS) core structures.
• Glycobiology Studies: A vital intermediate for investigating the pathways and enzymes involved in nucleotide-activated sugar metabolism and glycan assembly.
• Antibacterial Drug Discovery: Serves as a target molecule for screening and developing novel inhibitors that disrupt bacterial cell wall synthesis.
• Vaccine Development: Relevant for research into the structure and immunogenicity of bacterial LPS core antigens for conjugate vaccine design.
• Enzymology: Employed as a cofactor or substrate for characterizing the activity of specific transferases and synthases in bacterial systems.
• Metabolic Pathway Analysis: Used in tracer studies and metabolic profiling to understand bacterial survival and adaptation mechanisms.

Basic Information

Product Name	Adenosine 5'-Diphosphate-Glycero-Mannoheptose
CAS No.	80186-87-4
Molecular Formula	C17H27N5O19P2
Molecular Weight	667.36 g/mol
Synonyms	ADP-D-glycero-D-manno-heptose; ADP-Heptose; Adenosine 5'-(trihydrogen diphosphate), P'→7'-ester with D-glycero-D-manno-heptose; Adenosine diphosphate heptose; ADP-glyceromannoheptose; 5'-ADP-glycero-manno-heptose; Heptosyl-ADP; ADP-L-glycero-D-manno-heptose (isomer)
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Diphosphate-Glycero-Mannoheptose is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.