Description

1,2-Didecanoyl-3-Phosphatidic Acid is a synthetic phospholipid derivative, specifically a phosphatidic acid with defined decanoyl (C10) fatty acid chains. This compound is valued for its role as a key intermediate and model compound in lipid biochemistry and pharmaceutical research. It is primarily needed by researchers and manufacturers in the life sciences sector for studying lipid signaling pathways, membrane biophysics, and as a precursor for the synthesis of more complex phospholipids.

Application

• Lipidomics Research: Used as a standard or reference compound in mass spectrometry for the identification and quantification of phosphatidic acid species in biological samples.
• Biochemical Studies: Serves as a substrate or model lipid for investigating the activity of phospholipase D (PLD) and other lipid-modifying enzymes.
• Pharmaceutical Development: Acts as a critical intermediate in the synthesis of novel lipid-based drug delivery systems, such as liposomes and lipid nanoparticles (LNPs).
• Cell Signaling Research: Utilized to study the role of phosphatidic acid as a secondary messenger in cellular processes like membrane trafficking, cytoskeletal reorganization, and growth factor signaling.
• Membrane Biophysics: Employed in the creation of artificial lipid bilayers and vesicles to study membrane fluidity, phase behavior, and protein-lipid interactions.
• Cosmetic Science: Investigated for potential use in advanced skincare formulations for its emulsifying properties and role in skin barrier function.

Basic Information

Product Name	1,2-Didecanoyl-3-Phosphatidic Acid
CAS No.	80164-20-1
Molecular Formula	C23H45O8P
Molecular Weight	480.57 g/mol
Synonyms	PA(10:0/10:0); 1,2-Didecanoyl-sn-glycero-3-phosphate; Phosphatidic Acid(20:0); Decanoic acid, 1,2,3-propanetriyl ester, di-, mono(dihydrogen phosphate); 1,2-Dicaprinoyl-3-phosphatidic acid; sn-Glycerol-3-phosphate 1,2-didecanoate; 1,2-Didecanoyl-rac-glycero-3-phosphate
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-3-Phosphatidic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and structural integrity, with comprehensive Certificates of Analysis (COA) provided. While not intended for human therapeutic use as supplied, our quality systems support research and cGMP-grade manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in chloroform, methanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.