Description

1,2-Bis(4-(1-Pyreno)Butanoyl)-Sn-Glycero-3-Phosphorylcholine is a synthetic, pyrene-labeled phospholipid derivative designed for advanced research applications. This compound matters as a critical fluorescent probe for studying membrane dynamics, lipid-protein interactions, and cellular trafficking due to its strong pyrene excimer formation properties. It is essential for researchers and developers in biophysics, pharmaceutical formulation, and diagnostic assay development who require precise, high-purity tools for fluorescence spectroscopy and microscopy.

Application

• Fluorescent Membrane Probe: Used in biophysical studies to investigate lipid bilayer properties, phase transitions, and fusion events via pyrene excimer/monomer ratio analysis.
• Lipid-Protein Interaction Studies: Essential for probing the binding and activity of membrane-associated proteins, enzymes, and peptides in model membrane systems.
• Liposome & Drug Delivery Research: Serves as a traceable component in the development and characterization of liposomal formulations for targeted drug delivery.
• Cellular Imaging & Trafficking: Enables the visualization and tracking of lipid metabolism and intracellular vesicle transport pathways in live cells.
• Diagnostic Assay Development: Incorporated into sensor platforms and assay kits for detecting phospholipases or other lipid-modifying enzymes.
• Model Membrane Systems: A key component in creating defined, fluorescently-labeled lipid monolayers or bilayers for surface chemistry studies.

Basic Information

Product Name	1,2-Bis(4-(1-Pyreno)Butanoyl)-Sn-Glycero-3-Phosphorylcholine
CAS No.	80115-55-5
Molecular Formula	C58H64NO9P
Molecular Weight	950.10 g/mol
Synonyms	1,2-Di(4-(1-Pyrenyl)butanoyl)-sn-glycero-3-phosphocholine; Pyrene-PC; 1,2-Bis(4-(1-pyrenyl)butyryl)-sn-glycero-3-phosphocholine; Pyrene-labeled Phosphatidylcholine; 1,2-Dipyrenylbutanoyl Phosphatidylcholine; Fluorescent Phospholipid Probe; PBCPC; sn-Glycero-3-phosphocholine, 1,2-bis(4-(1-pyrenyl)butanoyl)-
EINECS	Contact for details

Quality Control

Our 1,2-Bis(4-(1-Pyreno)Butanoyl)-Sn-Glycero-3-Phosphorylcholine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, spectroscopic confirmation, and functional validation of fluorescence properties. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, DMSO, DMF
Fluorescence Properties	Excitation ~344 nm, Emission ~376 nm & 470 nm (excimer)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.