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4-Nitrophenyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside-6-Sulfatepotassiumsalt CAS NO 80095-44-9


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CAS No.:80095-44-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Nitrophenyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside-6-Sulfatepotassiumsalt is a specialized chromogenic substrate used in enzymatic assays. This compound is critical for the detection and quantification of specific sulfatase and glycosidase enzyme activities in biochemical research and diagnostic applications. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and clinical diagnostics sectors for high-precision analytical work.

Application

  • Enzymatic Substrate for Sulfatases: Used as a specific chromogenic substrate for the detection and kinetic study of N-acetylglucosamine-6-sulfate sulfatase and related enzymes.
  • Biochemical Research: Essential tool in enzyme characterization, inhibitor screening, and metabolic pathway analysis within academic and industrial R&D laboratories.
  • Diagnostic Kit Manufacturing: A key component in the formulation of diagnostic assays and kits for the detection of lysosomal storage disorders, such as certain mucopolysaccharidoses.
  • Pharmaceutical Quality Control: Employed in the quality control of enzyme-based therapeutics and in-process monitoring during biomanufacturing.
  • High-Throughput Screening (HTS): Suitable for use in automated HTS platforms for drug discovery programs targeting glycosidase enzymes.

Basic Information

Product Name 4-Nitrophenyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside-6-Sulfatepotassiumsalt
CAS No. 80095-44-9
Molecular Formula C14H17KN2O12S
Molecular Weight 492.46 g/mol
Synonyms p-Nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranoside 6-sulfate potassium salt; 4-Nitrophenyl N-acetyl-β-D-glucosaminide 6-sulfate potassium salt; PNP-β-GlcNAc-6-SO4 K salt; 6-Sulfo-4-nitrophenyl N-acetyl-β-D-glucosaminide potassium salt; NAG-6S; 4-Nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranoside-6-O-sulfate potassium salt; β-GlcNAc-6-S-PNP potassium salt
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Quality Control

Our 4-Nitrophenyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside-6-Sulfatepotassiumsalt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive biochemical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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