Description

Sigmamycin is a broad-spectrum antibiotic combination product, primarily consisting of tetracycline and oleandomycin. This synergistic formulation is valued for its enhanced efficacy against a wide range of Gram-positive and Gram-negative bacteria, offering a robust solution for complex infections. It is a critical raw material for the pharmaceutical industry, particularly in the formulation of veterinary medicines and specific human antibiotic preparations. The product, identified as CAS NO 8060-63-7, is supplied to manufacturers requiring high-purity active pharmaceutical ingredients (APIs) for reliable and effective end-products.

Application

• Pharmaceutical API: Primary use as an active pharmaceutical ingredient in the manufacture of broad-spectrum antibiotic formulations.
• Veterinary Medicine: Key component in medicated feeds, injectables, and topical treatments for livestock, poultry, and companion animals.
• Research & Development: Used in microbiological research, antimicrobial susceptibility testing, and development of new therapeutic combinations.
• Aquaculture: Employed in the treatment of bacterial infections in fish farming operations.
• Topical Preparations: Incorporated into ointments, creams, and powders for the treatment of skin and eye infections.
• Feed Additive: Used at prophylactic levels to prevent bacterial diseases and promote growth in animal husbandry (subject to regional regulations).

Basic Information

Product Name	Sigmamycin
CAS No.	8060-63-7
Molecular Formula	Mixture (C22H24N2O8 • C35H61NO12)
Molecular Weight	Mixture (444.44 g/mol • 687.87 g/mol)
Synonyms	Tetracycline-Oleandomycin Combination; Oleandomycin-Tetracycline; Antibiotic SI 4060; Signemycin; Tetramycin; Tetramycin-Oleandomycin; Signemycine; Signemycina
EINECS	Contact for details

Quality Control

Our Sigmamycin is produced and tested under a strict quality management system. Each batch is analyzed to ensure it meets stringent specifications for identity, potency, and purity, typical for pharmaceutical-grade materials. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and microbiological purity. Our quality commitment supports compliance with cGMP principles for API manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture to maintain stability and potency.

Specification

Item	Specification
Description	Yellow to light brown powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.