Description

Protoveratrines is a complex mixture of alkaloids derived from plants of the Veratrum species, primarily used as a reference standard and active pharmaceutical ingredient. This compound is valued for its potent biological activity, particularly in neurological and cardiovascular research. It is essential for pharmaceutical manufacturers, research institutions, and analytical laboratories engaged in the development and quality control of related therapeutic agents. The product is supplied with a CAS number of 8053-18-7.

Application

• Pharmaceutical Reference Standard: Serves as a primary chemical standard for the identification, assay, and purity testing of veratrum alkaloid-based pharmaceuticals.
• Active Pharmaceutical Ingredient (API): Used in the formulation of specific antihypertensive and neurological medications.
• Biochemical Research: Employed in pharmacological studies to investigate its effects on ion channels and cellular signaling pathways.
• Analytical Chemistry: Utilized as a calibrant in chromatographic methods (HPLC, LC-MS) for method development and validation.
• Toxicology Studies: Applied in research to understand the toxicological profile and mechanisms of veratrum alkaloids.

Basic Information

Product Name	Protoveratrines
CAS No.	8053-18-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Protoveratrine A and B mixture; Veratrum alkaloids; Protalba; Puroverine; Germitetrine; Germidine; Germitrine; Neogermitrine
EINECS	Contact for details

Quality Control

Our Protoveratrines is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the requirements for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (Total Protoveratrines)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.