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6-Mercaptopurine Arabinoside CAS NO 892-49-9


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CAS No.:892-49-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Mercaptopurine Arabinoside is a purine nucleoside analog with significant biochemical and pharmacological relevance. This compound is primarily valued as a key intermediate and reference standard in the research and development of novel chemotherapeutic agents. It is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on oncology and antiviral therapeutics.

Application

  • Pharmaceutical Intermediate: Critical building block in the synthesis of advanced nucleoside-based anticancer and antiviral drugs.
  • Biochemical Research: Used as a reference standard and tool compound in studies of purine metabolism, enzyme inhibition, and cell proliferation pathways.
  • Oncology R&D: Serves as a precursor or analog in the development of targeted therapies for leukemia and other malignancies.
  • Antiviral Agent Development: Investigated for its potential role in the synthesis of compounds with activity against viral infections.
  • Academic & Clinical Research: Employed in laboratory settings to study drug mechanisms of action, resistance, and metabolic fate.
  • Quality Control Standard: Utilized as a high-purity analytical standard for HPLC, LC-MS, and other methods in pharmaceutical quality assurance.

Basic Information

Product Name 6-Mercaptopurine Arabinoside
CAS No. 892-49-9
Molecular Formula C₁₀H₁₂N₄O₄S
Molecular Weight 284.29 g/mol
Synonyms 6-MP Arabinoside; 6-Mercaptopurine-9-β-D-arabinofuranoside; 9-β-D-Arabinofuranosyl-6-mercaptopurine; Ara-6-MP; NSC 49192; 6-Thiopurine Arabinoside; 6-Thio-9-β-D-arabinofuranosylpurine
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Quality Control

Our 6-Mercaptopurine Arabinoside is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle the material under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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