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6-Mercaptopurine Arabinoside CAS NO 892-49-9
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CAS No.:892-49-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Mercaptopurine Arabinoside is a purine nucleoside analog with significant biochemical and pharmacological relevance. This compound is primarily valued as a key intermediate and reference standard in the research and development of novel chemotherapeutic agents. It is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on oncology and antiviral therapeutics.
Application
- Pharmaceutical Intermediate: Critical building block in the synthesis of advanced nucleoside-based anticancer and antiviral drugs.
- Biochemical Research: Used as a reference standard and tool compound in studies of purine metabolism, enzyme inhibition, and cell proliferation pathways.
- Oncology R&D: Serves as a precursor or analog in the development of targeted therapies for leukemia and other malignancies.
- Antiviral Agent Development: Investigated for its potential role in the synthesis of compounds with activity against viral infections.
- Academic & Clinical Research: Employed in laboratory settings to study drug mechanisms of action, resistance, and metabolic fate.
- Quality Control Standard: Utilized as a high-purity analytical standard for HPLC, LC-MS, and other methods in pharmaceutical quality assurance.
Basic Information
| Product Name | 6-Mercaptopurine Arabinoside |
| CAS No. | 892-49-9 |
| Molecular Formula | C₁₀H₁₂N₄O₄S |
| Molecular Weight | 284.29 g/mol |
| Synonyms | 6-MP Arabinoside; 6-Mercaptopurine-9-β-D-arabinofuranoside; 9-β-D-Arabinofuranosyl-6-mercaptopurine; Ara-6-MP; NSC 49192; 6-Thiopurine Arabinoside; 6-Thio-9-β-D-arabinofuranosylpurine |
| EINECS | Contact for details |
Quality Control
Our 6-Mercaptopurine Arabinoside is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle the material under an inert atmosphere for long-term storage and to minimize headspace in opened containers.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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