Description

L-Serine β-Naphthylamide is a specialized biochemical reagent and a derivative of the amino acid L-serine, coupled with a β-naphthylamide moiety. This compound is primarily valued as a critical chromogenic substrate for the detection and quantification of specific proteolytic enzyme activities, particularly serine proteases. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science sectors who require precise enzymatic assays.

Application

• Enzymology Research: Used as a selective chromogenic substrate for studying the kinetics and inhibition of serine proteases like trypsin, chymotrypsin, and leukocyte elastase.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of diagnostic kits for detecting protease-related physiological conditions or bacterial contamination.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) assays to identify and evaluate potential protease inhibitor drug candidates.
• Biochemical Analysis: Utilized in laboratory protocols for the specific detection and measurement of protease activity in complex biological samples.
• Microbiology: Can be applied in tests to identify microorganisms based on their specific enzymatic profiles.
• Quality Control (QC): Acts as a reference standard or substrate in QC testing for enzyme purity and activity in biomanufacturing.

Basic Information

Item	Details
Product Name	L-Serine β-Naphthylamide
CAS No.	888-74-4
Molecular Formula	C₁₇H₁₈N₂O₂
Molecular Weight	282.34 g/mol
Synonyms	L-Serine β-naphthylamide; N-β-Naphthyl-L-serinamide; Serine β-naphthylamide; L-Ser-βNA; (S)-2-Amino-3-hydroxy-N-(naphthalen-2-yl)propanamide; N-(2-Naphthyl)-L-serinamide; β-naphthylamide of L-serine; Protease substrate
EINECS	212-958-9

Quality Control

Our L-Serine β-Naphthylamide is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high chemical purity and performance as a biochemical substrate. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity (typically by HPLC), and related substance profiles, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.