Description

(+/-)-Harmicine CAS NO 885-40-5 is a chiral alkaloid compound of significant interest in pharmaceutical research and development. This versatile intermediate is valued for its role in the synthesis of complex molecules and as a reference standard for analytical studies. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery and process chemistry. Our supply ensures high purity and batch-to-batch consistency critical for advanced applications.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate biological pathways and receptor interactions.
• Analytical Chemistry: Serves as a certified reference material (CRM) for method development, validation, and quality control in HPLC, LC-MS, and NMR analysis.
• Asymmetric Synthesis: Employed in the development of chiral catalysts and ligands for stereoselective reactions.
• Natural Product Chemistry: Used as a model compound in the study, synthesis, and structural modification of related alkaloids.

Basic Information

Product Name	(+/-)-Harmicine
CAS No.	885-40-5
Molecular Formula	C₁₃H₁₄N₂O
Molecular Weight	214.26 g/mol
Synonyms	Harmicine (racemic); 1-Methyl-4,9-dihydro-3H-β-carboline; 1-Methyl-1,2,3,4-tetrahydro-β-carboline; Tetrahydroharman; 1-Methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; Leptaflorine (racemate)
EINECS	Contact for details

Quality Control

Our (+/-)-Harmicine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, MS). We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports applications requiring high-purity reference standards and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.