Description

Thiolutin is a sulfur-containing heterocyclic antibiotic compound with significant biological activity. This versatile chemical is valued for its potent inhibitory effects against a broad spectrum of Gram-positive bacteria and fungi. It serves as a critical research tool and intermediate in the life sciences, pharmaceutical development, and agricultural chemistry sectors. Global industrial buyers rely on our supply for consistent quality and reliable material characterization.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in antimicrobial drug discovery.
• Agricultural Chemistry: Acts as a model compound for developing novel fungicides and bactericides to protect crops.
• Microbiological Studies: Serves as a selective agent in microbial genetics and biochemistry research to study bacterial transcription and cell function.
• Biochemical Reagent: Employed in laboratory settings as an inhibitor of RNA polymerase for mechanistic studies.
• Industrial Preservative: Potential application in formulations requiring control of microbial growth, subject to regional regulatory approval.

Basic Information

Product Name	Thiolutin
CAS No.	87-11-6
Molecular Formula	C8H8N2O2S2
Molecular Weight	228.29 g/mol
Synonyms	Acetopyrrothin; 4-Methyl-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one; Pyrrothine; NSC 17795; Antibiotic M 4209; Antibiotic PA 86; 1,2-Dithiolo[4,3-b]pyrrol-5(4H)-one, 4-methyl-
EINECS	201-727-9

Quality Control

Our Thiolutin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.