Description

Guanosine 5'-(Tetrahydrogen Triphosphate), commonly known as GTP, is a vital nucleotide that serves as a fundamental building block and energy currency in numerous biochemical pathways. Its primary commercial value lies in its essential role as a substrate for enzymatic reactions, energy transfer, and signal transduction processes. This high-purity biochemical is critical for researchers and manufacturers in the pharmaceutical, biotechnology, and molecular diagnostics sectors, where it is used in applications ranging from enzymatic synthesis to PCR and cell signaling studies.

Application

• Enzymatic Synthesis and Biocatalysis: As a high-energy phosphate donor for kinases and other ATP-dependent enzymes in the production of fine chemicals and active pharmaceutical ingredients (APIs).
• Molecular Biology Research: Essential component in in vitro transcription, translation systems, and PCR applications.
• Cell Signaling & Biochemical Assays: Used in G-protein coupled receptor (GPCR) research and as a substrate for GTPases in signal transduction studies.
• Diagnostic Reagent Manufacturing: Key raw material in the formulation of diagnostic kits for various diseases.
• Pharmaceutical Development: Utilized in drug discovery and development processes, particularly for targeting nucleotide-binding proteins.
• Biotechnology & Fermentation: Supplement in cell culture media to support metabolic processes and enhance protein expression.

Basic Information

Product Name	Guanosine 5'-(Tetrahydrogen Triphosphate)
CAS No.	86-01-1
Molecular Formula	C10H16N5O14P3
Molecular Weight	523.18 g/mol
Synonyms	GTP; Guanosine Triphosphate; 5'-GTP; Guanosine-5'-triphosphate; Guanyl triphosphate; Guanosine 5'-triphosphoric acid; 9-β-D-Ribofuranosylguanine-5'-triphosphate
EINECS	201-647-0

Quality Control

Our Guanosine 5'-(Tetrahydrogen Triphosphate) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and production applications. We provide material that meets or exceeds the standards required for molecular biology and pharmaceutical-grade applications. Comprehensive testing is performed, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep frozen. Allow the product to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Anhydrous basis)
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	3.0 - 5.0
Endotoxin (LAL)	< 10 EU/mg (for applicable grades)
Biological Activity	Tested in functional enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.