Description

6-Thioguanosine is a sulfur-containing nucleoside analog of guanosine, a key building block in nucleic acid research and pharmaceutical development. This compound is valued for its role as a biochemical precursor and its utility in studying RNA structure, function, and metabolism. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from antiviral and anticancer agent development to fundamental biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine metabolism and RNA processing.
• Nucleic Acid Chemistry: Employed in the study of RNA structure, function, and for incorporating thio-modifications into oligonucleotides.
• Life Science Reagents: A component in specialized cell culture media or diagnostic assay development for research purposes.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS methods.

Basic Information

Product Name	6-Thioguanosine
CAS No.	85-31-4
Molecular Formula	C10H13N5O4S
Molecular Weight	299.31 g/mol
Synonyms	6-Thioguanosine; 2-Amino-6-mercapto-9-β-D-ribofuranosylpurine; 6-Mercaptoguanosine; NSC 758; Guanosine, 6-thio-; 6-SG; 6-TG; 6-Thio-G
EINECS	201-593-9

Quality Control

Our 6-Thioguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.