Description

(3β)-17α-Hydroxyyohimban-16β-Carboxylic Acid Methyl Ester CAS NO 84-37-7 is a high-purity, complex indole alkaloid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its precise stereochemistry and structural framework, which is essential for producing specific bioactive molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical studies and the development of compounds targeting neurological pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Organic Synthesis: Employed in academic and industrial research for constructing intricate indole alkaloid structures.
• Biochemical Research: Utilized in studies investigating the interaction of alkaloids with biological systems.

Basic Information

Product Name	(3β)-17α-Hydroxyyohimban-16β-Carboxylic Acid Methyl Ester
CAS No.	84-37-7
Molecular Formula	C₂₁H₂₆N₂O₃
Molecular Weight	354.45 g/mol
Synonyms	Methyl (3β,16β,17α)-17-hydroxyyohimban-16-carboxylate; Methyl 17α-hydroxyyohimban-16β-carboxylate; Yohimbic acid methyl ester; 16β-Carbomethoxy-17α-hydroxyyohimban; Ajmalicine precursor; Raubasine intermediate; Tetrahydroalstonine related compound
EINECS	201-529-3

Quality Control

Our (3β)-17α-Hydroxyyohimban-16β-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.