Description

Tetryzoline is a synthetic imidazoline derivative with potent α-adrenergic agonist activity. This compound is a critical active pharmaceutical ingredient (API) valued for its vasoconstrictive and decongestant properties. It is primarily required by pharmaceutical manufacturers for the formulation of ophthalmic solutions and nasal sprays to relieve redness and congestion.

Application

• Ophthalmic Solutions: As the key active ingredient in eye drops for the temporary relief of redness due to minor eye irritation.
• Nasal Decongestants: Used in nasal spray formulations to provide relief from nasal congestion associated with allergies or colds.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of more complex therapeutic agents.
• Veterinary Medicines: Employed in topical preparations for animals to reduce localized swelling and irritation.
• Research & Development: Utilized in biochemical and pharmacological studies targeting adrenergic receptors.

Basic Information

Product Name	Tetryzoline
CAS No.	84-22-0
Molecular Formula	C13H16N2
Molecular Weight	200.28 g/mol
Synonyms	2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline; Tetrahydrozoline; Tetryzoline Hydrochloride (salt form); Tyzine; Visine (brand name component); Tetrahydrozoline HCl; 1,2,3,4-Tetrahydro-1-naphthalenyl-4,5-dihydro-1H-imidazole
EINECS	201-518-3

Quality Control

Our Tetryzoline is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical applications, with testing aligned with pharmacopeial methods. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.