Description

Theobromine CAS NO 83-67-0 is a bitter alkaloid of the methylxanthine class, naturally found in cocoa beans and other plants. It serves as a key intermediate and active ingredient in the synthesis of pharmaceuticals and nutraceuticals, valued for its diuretic, vasodilatory, and mild stimulant properties. This high-purity compound is essential for manufacturers in the pharmaceutical, food and beverage, and research and development sectors seeking reliable, specification-grade material for their formulations.

Application

• Pharmaceutical Intermediates: Primary use in the synthesis of APIs (Active Pharmaceutical Ingredients) for cardiovascular and respiratory medications.
• Nutraceutical & Dietary Supplements: Incorporated into energy, weight management, and cognitive health supplements for its mild stimulant effect.
• Food & Beverage Additive: Used as a bitter flavoring agent and functional component in specialty chocolate products and energy drinks.
• Research & Development: Serves as a standard reference material and key reagent in biochemical and pharmacological studies.
• Cosmetic Applications: Found in some skincare formulations for its potential vasodilatory and antioxidant properties.
• Chemical Synthesis: Acts as a building block for the production of other methylxanthine derivatives and fine chemicals.

Basic Information

Product Name	Theobromine
CAS No.	83-67-0
Molecular Formula	C7H8N4O2
Molecular Weight	180.16 g/mol
Synonyms	3,7-Dimethylxanthine; 3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione; Theobromin; Diurobromine; Santheose; Caffein, 7-methyl-; Theo-Dur; 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-
EINECS	201-494-2

Quality Control

Our Theobromine is produced under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and food-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%
Solubility	Sparingly soluble in water, soluble in alkali solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.