Description

Taurocholic Acid CAS NO 81-24-3 is a primary bile acid conjugate, formed from cholic acid and taurine, that plays a crucial role in lipid emulsification and absorption. This high-purity biochemical is essential for research and manufacturing processes requiring precise biological activity and structural integrity. It is primarily utilized by the pharmaceutical, life science, and diagnostic reagent industries for applications ranging from cell culture to drug formulation.

Application

• Pharmaceutical Intermediates: A key starting material or intermediate in the synthesis of therapeutic agents and other bile acid derivatives.
• Biochemical Research: Used as a critical reagent in studies of lipid metabolism, hepatocyte function, and bile acid receptor signaling (e.g., FXR, TGR5).
• Cell Culture & Media Supplement: Employed as a component in specialized cell culture media, particularly for hepatocytes and other liver-derived cell lines, to maintain physiological function.
• Diagnostic Reagents: Serves as a standard or reference compound in clinical diagnostic kits for liver function and bile acid metabolism disorders.
• Micelle & Liposome Formation: Acts as a natural, biocompatible surfactant for creating micelles and liposomes in drug delivery system development.
• Enzyme Activity Studies: Used as a substrate or effector in enzymatic assays related to digestive and metabolic pathways.

Basic Information

Product Name	Taurocholic Acid
CAS No.	81-24-3
Molecular Formula	C26H45NO7S
Molecular Weight	515.70 g/mol
Synonyms	Cholyltaurine; Taurocholate; N-Choloyltaurine; 3α,7α,12α-Trihydroxy-5β-cholan-24-oyltaurine; Taurine-conjugated cholic acid; Sodium taurocholate (salt form); TCA
EINECS	201-337-8

Quality Control

Our Taurocholic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 10 ppm
Specific Optical Rotation	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.