Description

Octanoyl Coenzyme A (Ammonium Salt) is a critical biochemical reagent, specifically an activated form of octanoic acid (C8) esterified to coenzyme A. This compound matters as a key metabolic intermediate in fatty acid oxidation (β-oxidation) and biosynthesis pathways, enabling essential energy production and lipid metabolism studies. Researchers and manufacturers in pharmaceutical development, metabolic disease research, and enzymology require high-purity Octanoyl CoA for reliable, reproducible results in assays and enzymatic studies.

Application

• Enzymatic Research & Assay Development: Essential substrate for studying acyl-CoA dehydrogenases, thioesterases, and other enzymes involved in mitochondrial fatty acid β-oxidation.
• Metabolic Pathway Analysis: Used in vitro to investigate lipid metabolism, energy homeostasis, and disorders like medium-chain acyl-CoA dehydrogenase (MCAD) deficiency.
• Pharmaceutical Screening: Serves as a target or tool compound in drug discovery programs focused on metabolic diseases, cancer metabolism, and rare genetic disorders.
• Biochemical Synthesis: Acts as a building block for the enzymatic synthesis of more complex lipids, surfactants, or labeled compounds for tracer studies.
• Diagnostic Kit Manufacturing: A key component in clinical diagnostic kits designed to measure specific enzyme activities or metabolic biomarkers in patient samples.
• Academic & Institutional Research: Fundamental reagent for university and research institute labs focused on biochemistry, cell biology, and molecular nutrition.

Basic Information

Product Name	Octanoyl Coenzyme A (Ammonium Salt)
CAS No.	799812-82-1
Molecular Formula	C29H54N7O17P3S • xNH3
Molecular Weight	Approx. 921.7 g/mol (Free acid)
Synonyms	Octanoyl-CoA; Octanoyl-Coenzyme A; C8:0-CoA; Coenzyme A, S-octanoate; Octanoyl CoA ammonium salt; Medium-chain acyl-CoA; Capryloyl-Coenzyme A; S-Octanoylcoenzyme A
EINECS	Contact for details

Quality Control

Our Octanoyl Coenzyme A (Ammonium Salt) is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to ISO 9001 quality management principles, and our processes support development under cGMP guidelines for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., argon or nitrogen) and allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% (by acyl-CoA dehydrogenase)
Water Content (KF)	≤ 5%
Solubility	Clear, colorless solution in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.