Description

1,2-Dioleoyl-Sn-Glycero-3-(Cytidine Diphosphate) (Ammonium Salt) is a high-purity, synthetic phospholipid derivative of cytidine diphosphate, essential for advanced biochemical and pharmaceutical research. This compound serves as a critical building block for the enzymatic synthesis of complex phospholipids and glycoconjugates within artificial membrane systems. It is primarily utilized by researchers and developers in lipidomics, drug delivery system development, and enzyme mechanism studies, where precise molecular structure and purity are paramount for reproducible results.

Application

• Enzymatic Synthesis Substrate: A key precursor for the enzymatic production of phosphatidylinositol and other signaling phospholipids in vitro.
• Lipid Nanoparticle (LNP) Research: Used in the development and optimization of novel lipid formulations for nucleic acid (e.g., mRNA, siRNA) delivery.
• Membrane Biophysics Studies: Essential for constructing model lipid bilayers and vesicles to study membrane protein interactions and dynamics.
• Glycobiology & Glycoengineering: Acts as a donor substrate for glycosyltransferases in the synthesis of glycosylphosphatidylinositol (GPI) anchors.
• Biochemical Assay Development: Employed in high-throughput screening assays for enzymes like CDP-diacylglycerol synthases and related transferases.
• Reference Standard: Serves as an analytical standard in LC-MS/MS for the quantification of phospholipid pathways in metabolic studies.

Basic Information

Item	Details
Product Name	1,2-Dioleoyl-Sn-Glycero-3-(Cytidine Diphosphate) (Ammonium Salt)
CAS No.	799812-77-4
Molecular Formula	C52H93N4O16P2 • xNH3
Molecular Weight	~1107.3 g/mol (Free acid, C52H93N4O16P2)
Synonyms	CDP-Diacylglycerol (18:1); CDP-Dioleoylglycerol; Cytidine Diphosphate Dioleoylglycerol; 1,2-Dioleoyl-sn-glycero-3-cytidine-5'-diphosphate ammonium salt; CDP-DOG; CDP-DAG (18:1/18:1); C18:1 CDP-DAG; O-[(2R)-2,3-Bis[[(Z)-octadec-9-enoyl]oxy]propyl] cytidine-5'-(trihydrogen diphosphate) ammonium salt
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Dioleoyl-Sn-Glycero-3-(Cytidine Diphosphate) (Ammonium Salt) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent internal quality standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC and MS is provided with each shipment to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area Percent)
Assay (HPLC/UV)	≥ 90% (by anhydrous weight)
Solubility	Soluble in chloroform, methanol; slightly soluble in water
Water Content (KF)	≤ 5.0 % w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.