Description

1-(12-n-Biotin)Aminododecanoyl-Rac-Glycerol is a specialized synthetic lipid derivative that incorporates biotin (vitamin B7) via a long-chain aminododecanoyl linker. This molecular design is critical for creating biotinylated lipid probes and conjugates with enhanced stability and specific binding affinity. It is primarily utilized by researchers and manufacturers in the life sciences sector who require precise tools for studying lipid metabolism, membrane biology, and targeted drug delivery systems. The compound's unique structure makes it an essential intermediate for developing advanced diagnostic and therapeutic agents.

Application

• Lipidomics Research: Used as a critical standard or probe for the study of glycerolipid metabolism and signaling pathways.
• Biotin-Avidin Technology: Serves as a key building block for synthesizing biotinylated lipids, enabling strong, specific binding to avidin/streptavidin in assay development and diagnostics.
• Liposome & Nanoparticle Functionalization: Incorporated into lipid bilayers to create targeted delivery vehicles for drugs, genes, or imaging agents.
• Membrane Protein Studies: Facilitates the labeling and isolation of membrane-associated proteins through biotin-streptavidin interactions.
• Bioconjugation & Cross-linking: Acts as a versatile intermediate for coupling biotin to other biomolecules or surfaces in sensor and microarray fabrication.
• Pharmaceutical Intermediate: Employed in the research and development of novel lipid-based therapeutic compounds.

Basic Information

Product Name	1-(12-n-Biotin)Aminododecanoyl-Rac-Glycerol
CAS No.	799812-64-9
Molecular Formula	C30H55N3O6S
Molecular Weight	585.85 g/mol
Synonyms	1-(12-Biotinylamino)dodecanoyl-rac-glycerol; Biotinylaminododecanoylglycerol; rac-Glycerol 1-[12-[(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl)amino]dodecanoate]; Biotinylated Lipid; N-Biotinyl-12-aminododecanoyl-rac-glycerol; Vitamin H Lipid Conjugate; Biotin-LC-Glycerol; D-Biotin N-dodecanoyl-rac-glycerol ester
EINECS	Contact for details

Quality Control

Our 1-(12-n-Biotin)Aminododecanoyl-Rac-Glycerol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical manufacturing, and custom synthesis and purification to specific customer specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.