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1-o-Octadecyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) CAS NO 799279-67-7


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CAS No.:799279-67-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-o-Octadecyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) is a high-purity synthetic phospholipid derivative, specifically a lysophosphatidic acid (LPA) analogue with a long-chain alkyl group. This compound is a critical biochemical tool and a key intermediate for advanced research and development in life sciences. It is primarily utilized by pharmaceutical researchers, formulation scientists, and biochemists working on lipid-based drug delivery systems, cell signaling studies, and the development of novel therapeutic agents.

Application

  • Lipid Nanoparticle (LNP) Formulation: As a functional excipient or structural component in the development of mRNA and siRNA delivery vehicles.
  • Biochemical Research: As a standard, substrate, or modulator in studies of lysophosphatidic acid (LPA) receptor signaling pathways and lipid metabolism.
  • Pharmaceutical Intermediates: Serving as a key building block for the synthesis of more complex phospholipids and prodrugs.
  • Cell Culture & Membrane Studies: Used to modify membrane properties or as a component in synthetic membrane models (e.g., liposomes, bilayers).
  • Diagnostic Reagent Development: As a component in assay kits for enzyme activity (e.g., phospholipases) or lipid detection.
  • Cosmetic & Dermal Formulations: As a bioactive ingredient in high-end skincare products for its potential cell-communicating and barrier-enhancing properties.

Basic Information

Product Name 1-o-Octadecyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt)
CAS No. 799279-67-7
Molecular Formula C21H48NO6P
Molecular Weight 441.58 g/mol
Synonyms 1-Octadecyl-2-hydroxy-sn-glycero-3-phosphate ammonium salt; 1-Stearyl-2-hydroxy-sn-glycero-3-phosphate ammonium salt; LysoPA(18:0/0:0) ammonium salt; LPA 18:0 ammonium salt; 1-O-Octadecyl-2-hydroxy-sn-glycerol-3-phosphate ammonium salt; Ammonium 1-octadecyl-2-hydroxy-sn-glycero-3-phosphate; 1-Octadecyl-lysophosphatidic acid ammonium salt
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Quality Control

Our 1-o-Octadecyl-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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