Description

1-o-Hexadecyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt) is a synthetic, high-purity phospholipid derivative with a unique cyclic phosphate headgroup. This compound is a critical building block and intermediate in advanced lipid research and pharmaceutical development. It is primarily utilized by R&D scientists and process chemists in the life sciences sector for creating novel drug delivery systems, such as liposomal formulations, and for studying membrane biophysics.

Application

• Liposomal Drug Delivery: A key phospholipid component for formulating stable, targeted liposomes for cancer therapeutics, vaccines, and nucleic acid delivery.
• Pharmaceutical Intermediates: Serves as a crucial synthetic intermediate in the production of more complex, bioactive phospholipids and prodrugs.
• Biomimetic Membrane Research: Used to construct model cell membranes (e.g., vesicles, bilayers) for studying protein-lipid interactions, permeability, and signaling.
• Bioconjugation & Labeling: The reactive cyclic phosphate and amino groups provide handles for attaching targeting ligands, dyes, or other functional molecules.
• Excipient Development: Investigated as a novel excipient to enhance the solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Diagnostic Reagents: Potential use in the development of diagnostic assays and imaging agents that require specific membrane anchoring.

Basic Information

Product Name	1-o-Hexadecyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt)
CAS No.	799268-68-1
Molecular Formula	C19H42NO5P
Molecular Weight	395.51 g/mol
Synonyms	1-O-Hexadecyl-2,3-cyclic glycerophosphate ammonium salt; 1-O-Hexadecyl-sn-glycerol 2,3-cyclic phosphate ammonium salt; C16 LysoPA cyclic ammonium salt; Hexadecyl cyclic lysophosphatidic acid ammonium salt; cPA(16:0)-NH4; Ammonium 1-O-hexadecyl-sn-glycero-2,3-cyclic phosphate; 1-O-Cetyl-sn-glycero-2,3-cyclic phosphate ammonium salt
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.