Description

Omega(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)(2S,3R,4E)-2-Aminooctadec-4-Ene-1,3-Diol CAS NO 799268-47-6 is a sophisticated, fluorescently labeled sphingolipid derivative, specifically designed for advanced biochemical research. This compound is critical for studying lipid metabolism, membrane dynamics, and intracellular signaling pathways with high sensitivity. It is an essential tool for researchers and scientists in the fields of lipidomics, cell biology, and pharmaceutical development, enabling precise tracking and analysis within complex biological systems.

Application

• Fluorescent Labeling in Lipid Research: Acts as a vital fluorescent probe for tracing and visualizing sphingolipid metabolism, transport, and localization in live cells and tissues.
• Biochemical Assay Development: Used as a key substrate or standard in enzymatic assays to study the activity of ceramidases, sphingomyelinases, and other lipid-modifying enzymes.
• Membrane Biology Studies: Employed to investigate lipid raft formation, membrane fluidity, and protein-lipid interactions due to its specific incorporation into cellular membranes.
• Drug Discovery & Pharmacology: Serves as a critical tool in high-throughput screening (HTS) campaigns and mechanistic studies for drugs targeting sphingolipid-related diseases like cancer, neurodegeneration, and metabolic disorders.
• Diagnostic Reagent Component: Can be utilized in the development of sensitive diagnostic kits for detecting enzymatic deficiencies or metabolic pathway dysregulation.
• Academic & Industrial R&D: Essential for fundamental research in universities and applied research in biotech and pharmaceutical companies focused on lipid signaling pathways.

Basic Information

Product Name	Omega(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)(2S,3R,4E)-2-Aminooctadec-4-Ene-1,3-Diol
CAS No.	799268-47-6
Molecular Formula	C30H48N4O5
Molecular Weight	544.73 g/mol
Synonyms	NBD C6-Ceramide; NBD-Ceramide (d18:1/6:0); 6-[(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoyl]sphingosine; N-[6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine; Fluorescent Ceramide NBD C6; NBD C6-Cer (d18:1/6:0); NBD Hexanoyl Sphingosine; NBD-Cer
EINECS	Contact for details

Quality Control

Our high-purity biochemical reagents are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry for identity confirmation, and fluorescence spectroscopy to ensure performance specifications are met. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~465 nm (in methanol)
Emission Maximum (λem)	~535 nm (in methanol)
Solubility	Soluble in DMSO, ethanol, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.