Description

L-α-Phosphatidylglycerol (E. Coli) (Sodium Salt) is a high-purity, natural phospholipid derived from *Escherichia coli* membranes, serving as a critical building block for advanced lipid-based formulations. This compound is essential for researchers and manufacturers requiring a defined, biologically relevant lipid source for creating model membranes and delivery systems. It is particularly valuable in the pharmaceutical and biotechnology sectors for developing liposomal drug carriers, vaccine adjuvants, and in fundamental membrane biophysics research.

Application

• Liposomal Drug Delivery Systems: A key component for formulating stable, biocompatible liposomes for targeted and sustained release of therapeutic agents.
• Vaccine Adjuvant Development: Used in research to create novel lipid-based adjuvants that can enhance immune response.
• Biomimetic Membrane Models: Essential for constructing artificial membranes to study protein-lipid interactions, membrane fusion, and permeability.
• Pulmonary Surfactant Research: Investigated as a component in synthetic lung surfactant formulations for treating respiratory distress syndrome.
• Cell Culture & Media Supplements: Employed in specialized cell culture applications to support membrane integrity and function.
• Diagnostic Reagents: Utilized in the development of lipid-based assays and diagnostic kits.

Basic Information

Product Name	L-α-Phosphatidylglycerol (E. Coli) (Sodium Salt)
CAS No.	796963-92-3
Molecular Formula	C42H80NaO10P (for a common species with 16:0/16:0 fatty acyl chains)
Molecular Weight	~807.0 g/mol (for 16:0/16:0 species)
Synonyms	PG (E. coli, Sodium Salt); 1,2-Diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) (Sodium Salt); Phosphatidylglycerol, Sodium Salt; E. coli PG-Na; PG-Na; 3-sn-Phosphatidyl-1'-sn-glycerol; Bacterial Phosphatidylglycerol; Cardiolipin precursor
EINECS	Contact for details

Quality Control

Our L-α-Phosphatidylglycerol (E. Coli) (Sodium Salt) is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and lipid species profile, to ensure consistency and meet the stringent requirements of research and formulation applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). The product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to standard
Assay (HPLC)	≥ 95% (Total Phosphatidylglycerol)
Fatty Acid Composition (GC)	Predominantly C16:0, C18:1 (E. coli profile)
Water Content (KF)	≤ 3.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.