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(R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(4-Nitrophenyl)-[1,1'-Binaphthalene]-2,2'-Diol CAS NO 791616-67-6
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CAS No.:791616-67-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(4-Nitrophenyl)-[1,1'-Binaphthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative, distinguished by its unique (R)-configuration and substituted nitroaryl groups. This compound serves as a critical chiral ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.
Application
- Asymmetric Catalysis: As a chiral ligand for transition metal complexes (e.g., with Ru, Rh, Pd) in enantioselective hydrogenation, C-C bond formation, and other key transformations.
- Pharmaceutical Intermediate Synthesis: For the research and production of chiral active pharmaceutical ingredients (APIs) where high enantiomeric purity is mandated.
- Chiral Resolution Agent: Utilized in the separation of racemic mixtures to isolate desired enantiomers.
- Advanced Material Research: As a building block for chiral polymers, liquid crystals, or molecular recognition systems.
- Agrochemical Development: In the synthesis of enantiomerically pure herbicides, fungicides, or plant growth regulators.
- Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry.
Basic Information
| Product Name | (R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(4-Nitrophenyl)-[1,1'-Binaphthalene]-2,2'-Diol |
| CAS No. | 791616-67-6 |
| Molecular Formula | C32H28N2O6 |
| Molecular Weight | 536.58 g/mol |
| Synonyms | (R)-H8-BINOL-3,3'-dinitro; (R)-Octahydro-3,3'-bis(4-nitrophenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Bis(4-nitrophenyl)-H8-BINOL; (R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-di-p-nitrophenyl-2,2'-dihydroxy-1,1'-binaphthyl; (R)-H8-3,3'-Dinitro-BINOL; (R)-3,3'-Dinitro-H8-BINOL; Chiral NO2-H8-BINOL Derivative |
| EINECS | Contact for details |
Quality Control
Our production of this chiral compound adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Identity, purity, and chiral integrity are verified using advanced analytical techniques including HPLC, NMR, and chiral chromatography. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to light brown powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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