Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, Methyl Ester, (1R,2R)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its unique cyclopropane ring fused with an amino ester functional group, making it a critical building block for constructing complex, biologically active molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and the development of novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The amino ester functionality makes it valuable for constructing conformationally restricted peptide analogs in medicinal chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, Methyl Ester, (1R,2R)- (9Ci)
CAS No.	772326-49-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1R,2R)-1-Amino-2-ethylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2R)-1-amino-2-ethylcyclopropanecarboxylate; (1R,2R)-1-Amino-2-ethylcyclopropanecarboxylic acid methyl ester; (1R,2R)-AECM; (1R,2R)-1-Amino-2-ethyl-cyclopropanecarboxylic acid methyl ester; trans-1-Amino-2-ethylcyclopropanecarboxylic acid methyl ester; (1R,2R)-1-AECM
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, Methyl Ester, (1R,2R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.