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Oxymorphone 3-B-D-Glucuronide CAS NO 770735-01-8
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CAS No.:770735-01-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Oxymorphone 3-B-D-Glucuronide is a major, inactive metabolite of the potent opioid analgesic oxymorphone. This compound is of critical importance in forensic and clinical toxicology for the definitive identification and quantification of oxymorphone use. It is primarily required by analytical laboratories, pharmaceutical research facilities, and diagnostic manufacturers engaged in drug monitoring, abuse deterrence studies, and the development of reference standards for accurate testing protocols.
Application
- Reference Standard for Toxicology: Serves as a certified reference material (CRM) for the precise calibration of analytical instruments like LC-MS/MS and GC-MS in forensic and workplace drug testing.
- Clinical Research & Metabolite Studies: Used in pharmacokinetic and metabolic pathway research to understand the biotransformation and elimination profile of oxymorphone.
- Pharmaceutical Impurity Profiling: Employed as an analytical standard to identify and quantify this specific glucuronide metabolite during drug development and quality control of oxymorphone-based pharmaceuticals.
- Diagnostic Kit Development: A key component in the formulation and validation of immunoassays and other diagnostic tests designed to detect oxymorphone use in biological matrices.
- Forensic Analysis & Legal Evidence: Provides definitive, confirmatory evidence in post-mortem toxicology and legal cases involving substance use.
- Academic Research: Utilized in university and institutional research focusing on opioid metabolism, detection methodologies, and pharmacological studies.
Basic Information
| Item | Details |
|---|---|
| Product Name | Oxymorphone 3-B-D-Glucuronide |
| CAS No. | 770735-01-8 |
| Molecular Formula | C24H29NO10 |
| Molecular Weight | 491.49 g/mol |
| Synonyms | 14-Hydroxydihydromorphinone 3-glucuronide; Oxymorphone 3-Glucuronide; 3-Glucuronide of Oxymorphone; Noroxymorphone Glucuronide (related); Oxymorphone Glucuronide Metabolite; 4,5α-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one 3-β-D-glucuronide; 14-Hydroxydihydromorphinone-3-β-D-glucopyranosiduronic acid |
| EINECS | Contact for details |
Quality Control
Our Oxymorphone 3-B-D-Glucuronide is manufactured and handled under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and compliance.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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