Description

Meosuc-Lys(2-Picolinoyl)-Ala-Pro-Val-Pna is a synthetic peptide derivative, specifically designed as a chromogenic substrate for the study of proteolytic enzymes. This compound matters for researchers and developers in life sciences as it provides a reliable and sensitive tool for monitoring enzyme activity, particularly for serine proteases. It is primarily needed by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic biochemistry laboratories focused on enzyme kinetics, inhibitor screening, and assay development.

Application

• Protease Activity Assays: Primary substrate for the quantitative measurement of specific serine protease activity in biochemical research.
• Enzyme Inhibitor Screening: Used in high-throughput screening (HTS) platforms to identify and characterize potential therapeutic protease inhibitors.
• Diagnostic Reagent Development: A key component in the formulation of chromogenic tests for clinical diagnostics and research use only (RUO) kits.
• Biochemical Research: Employed in studying enzyme kinetics, mechanism of action, and substrate specificity profiles.
• Pharmaceutical Quality Control: Utilized in potency testing and stability studies of biopharmaceutical products involving proteases.

Basic Information

Product Name	Meosuc-Lys(2-Picolinoyl)-Ala-Pro-Val-Pna
CAS No.	757139-27-8
Molecular Formula	C36H48N8O9
Molecular Weight	736.82 g/mol
Synonyms	MeOSuc-AAPV-pNA; Methoxysuccinyl-Ala-Ala-Pro-Val-p-Nitroanilide; MeOSuc-Ala-Ala-Pro-Val-pNA; Chromogenic Substrate for Human Neutrophil Elastase (HNE); Suc-AAPV-pNA analog; Protease Substrate 757139-27-8; pNA-based elastase substrate; N-Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide
EINECS	Contact for details

Quality Control

Our Meosuc-Lys(2-Picolinoyl)-Ala-Pro-Val-Pna is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.