Description

Spiro[Bicyclo[3.2.1]Octane-8,3-[3H]Diazirin]-3-Ol, (1Alpha,3Beta,5Alpha)- (9Ci) is a specialized, high-purity organic compound featuring a unique spiro-fused diazirine and bicyclic octane structure. This compound is of significant value as a versatile photoaffinity labeling reagent and a key synthetic intermediate in advanced organic synthesis. It is primarily needed by research institutions and pharmaceutical companies engaged in proteomics, drug discovery, and chemical biology for mapping biomolecular interactions and developing novel therapeutic agents.

Application

• Photoaffinity Labeling (PAL): As a critical reagent for covalent cross-linking in target identification and binding site mapping studies.
• Chemical Probe Synthesis: For the development of activity-based probes to study enzyme function and protein networks.
• Pharmaceutical Intermediate: In the synthesis of complex, biologically active molecules for drug discovery pipelines.
• Bioconjugation: For site-specific labeling of proteins, peptides, and other biomolecules.
• Materials Science Research: As a building block for novel polymers or functional materials requiring specific photochemical properties.
• Academic & Industrial R&D: For fundamental research in organic reaction mechanisms and the development of new synthetic methodologies.

Basic Information

Item	Detail
Product Name	Spiro[Bicyclo[3.2.1]Octane-8,3-[3H]Diazirin]-3-Ol, (1Alpha,3Beta,5Alpha)- (9Ci)
CAS No.	724762-24-7
Molecular Formula	C9H14N2O
Molecular Weight	166.22 g/mol
Synonyms	(1α,3β,5α)-Spiro[bicyclo[3.2.1]octane-8,3'-[3H]diazirin]-3-ol; 3-Hydroxyspiro[bicyclo[3.2.1]octane-8,3'-[3H]diazirine]; Diazirine-based photoaffinity label; Bicyclo[3.2.1]octane diazirin-3-ol; Photoactivatable crosslinker; PAL reagent; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere for long-term stability. This compound is strictly light-sensitive and must be handled under subdued light or in amber glass to prevent decomposition. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.