Description

Qsy 9 Carboxylic Acid, Succinimidyl Ester is a reactive amine-reactive ester derivative, widely used as a key intermediate and labeling reagent in advanced bioconjugation chemistry. Its primary value lies in enabling the efficient, site-specific coupling of Qsy 9 fluorescent dye molecules to proteins, peptides, antibodies, and other biomolecules containing primary amine groups. This product is essential for researchers and manufacturers in the fields of biopharmaceutical development, diagnostic assay production, and advanced life science research, where reliable and high-purity conjugation reagents are critical.

Application

• Bioconjugation & Protein Labeling: Primary application for covalently attaching the Qsy 9 near-infrared fluorophore to antibodies, proteins, and peptides for imaging and detection.
• Diagnostic Reagent Manufacturing: Used in the synthesis of fluorescent probes and conjugates for ELISA, lateral flow assays, and other in vitro diagnostic (IVD) kits.
• Biopharmaceutical Research: Enables the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents where a near-infrared reporter is required.
• Molecular Imaging Probe Synthesis: Key building block for creating targeted imaging agents used in preclinical and research settings for fluorescence microscopy and in vivo imaging.
• Life Science Research Tools: Employed to label biomolecules for studying protein-protein interactions, cellular localization, and biochemical pathways.
• Material Science Functionalization: Used to introduce fluorescent properties onto nanoparticles, polymers, or surfaces for sensing and tracking applications.

Basic Information

Product Name	Qsy 9 Carboxylic Acid, Succinimidyl Ester
CAS No.	700834-40-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	QSY 9 NHS Ester; QSY® 9 Carboxylic Acid, Succinimidyl Ester; Succinimidyl ester of Qsy 9 carboxylic acid; N-Hydroxysuccinimide ester of Qsy 9 dye; Qsy 9 SE; Qsy 9-NHS; Near-infrared dye NHS ester; Amine-reactive Qsy 9 derivative
EINECS	Contact for details

Quality Control

Our Qsy 9 Carboxylic Acid, Succinimidyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic confirmation of structure. Certificates of Analysis (COA) detailing all relevant specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMF, DMSO, acetonitrile
Moisture Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.