Description

5-Fluorouridine Diphosphate Glucose is a fluorinated nucleotide sugar derivative, a key biochemical intermediate in specialized metabolic pathways. This compound is critical for researchers and manufacturers developing novel antiviral agents and metabolic probes, as its structure allows for targeted inhibition and labeling. It is primarily utilized in pharmaceutical R&D, biochemistry, and molecular biology for studying glycosylation processes and enzyme mechanisms.

Application

• Pharmaceutical Research & Development: Serves as a crucial precursor or intermediate in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Studies: Used as a substrate or inhibitor for glycosyltransferase enzymes to study carbohydrate metabolism and glycosylation pathways.
• Probe Development: Acts as a building block for creating fluorescent or radiolabeled probes to track nucleotide sugar utilization in cellular systems.
• Enzymology: Employed in kinetic assays and mechanistic studies of enzymes involved in nucleotide-sugar biosynthesis and transfer.
• Glycobiology Research: Essential for investigating the role of fluorinated sugar nucleotides in altering glycan structures and functions.
• Antiviral Agent Synthesis: A key intermediate for the development of potential therapeutics targeting viral polymerases and replication mechanisms.

Basic Information

Product Name	5-Fluorouridine Diphosphate Glucose
CAS No.	79965-09-6
Molecular Formula	C15H21FN2O16P2
Molecular Weight	566.28 g/mol
Synonyms	5-Fluorouridine 5'-diphosphoglucose; 5-Fluoro-UDP-glucose; UDP-5-Fluoroglucose; 5-Fluoro-uridine diphosphate glucose; 5-Fluorouridine 5'-(trihydrogen diphosphate) P'→5'-ester with D-glucose; 5-F-UDP-Glc; 5-Fluorouridine 5'-diphospho-α-D-glucose
EINECS	Contact for details

Quality Control

Every batch of 5-Fluorouridine Diphosphate Glucose is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.