Description

Carboxymethyl-Coenzyme A is a key biochemical intermediate and a modified coenzyme A derivative. This compound is essential for researchers studying enzymatic mechanisms, metabolic pathways, and the biosynthesis of various natural products. It is primarily utilized in life science research, pharmaceutical development, and as a critical reagent in biochemical assays and enzymatic synthesis.

Application

• Enzymology Research: Used as a substrate or intermediate in studies of acyltransferase and other CoA-dependent enzymes.
• Metabolic Pathway Analysis: Investigates the role of carboxymethyl-CoA in specialized biosynthetic pathways.
• Pharmaceutical Development: Serves as a building block or precursor in the research and synthesis of novel therapeutic agents.
• Biochemical Assays: Employed as a standard or reagent in high-throughput screening and diagnostic test development.
• Natural Product Biosynthesis: A key intermediate in the study and engineered production of complex microbial metabolites.
• Academic & Industrial R&D: Fundamental research tool in universities and biotechnology companies for exploring new enzymatic functions.

Basic Information

Product Name	Carboxymethyl-Coenzyme A
CAS No.	79955-48-9
Molecular Formula	C23H38N7O19P3S
Molecular Weight	897.55 g/mol
Synonyms	Carboxymethyl-CoA; S-Carboxymethyl-CoA; Coenzyme A, S-(carboxymethyl) derivative; 3'-Phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(sulfanylmethyl)carbamoyl]ethyl}amino)butyl]amino}butyl dihydrogen diphosphate); (R)-4-({3-[(2-{[(2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl)oxy)-2-hydroxy-3,3-dimethylbutanoyl]amino}-3-oxopropyl)-2-(carboxymethylsulfanyl)acetamide
EINECS	Contact for details

Quality Control

Our Carboxymethyl-Coenzyme A is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic/UV)	≥ 90%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.