Description

Maleimidomethyl-3-Maleimido Propionate CAS NO 79951-01-2 is a heterobifunctional crosslinking agent featuring two distinct maleimide groups, enabling the selective conjugation of thiol-containing molecules. This compound is essential for creating stable, site-specific linkages in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and polymer industries for developing antibody-drug conjugates (ADCs), functionalized surfaces, and specialty polymers.

Application

• Bioconjugation reagent for the site-specific coupling of peptides, proteins, and antibodies.
• Critical intermediate in the synthesis of Antibody-Drug Conjugates (ADCs) and other targeted therapeutics.
• Surface functionalization of nanoparticles, biosensors, and chromatographic media.
• Crosslinking agent in the development of hydrogels and specialty polymers with tailored properties.
• Tool compound for protein structure studies and immobilization techniques.
• Modification of oligonucleotides and other biomolecules for diagnostic assay development.

Basic Information

Product Name	Maleimidomethyl-3-Maleimido Propionate
CAS No.	79951-01-2
Molecular Formula	C11H10N2O6
Molecular Weight	266.21 g/mol
Synonyms	3-Maleimidopropionic Acid N-(2-Maleimidoethyl)amide; 1,1'-[1,3-Propanediylbis(oxy-2,1-ethanediyl)]bismaleimide; BMPS; 3-Maleimidopropionic Acid 2-(2-Maleimidoethoxy)ethyl Ester; N-(2-Maleimidoethyl)-3-maleimidopropionamide; Maleimidomethyl-3-maleimidopropanoate; Bifunctional Maleimide Crosslinker; Heterobifunctional Maleimide Linker
EINECS	Contact for details

Quality Control

Our Maleimidomethyl-3-Maleimido Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, Acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.