Description

Leukotriene D5 is a potent bioactive lipid mediator belonging to the cysteinyl leukotriene family, identified by CAS NO 79695-13-9. It plays a critical role in inflammatory and allergic response pathways, making it an essential reference standard and research tool for understanding physiological and pathological processes. This high-purity compound is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on respiratory diseases, immunology, and inflammation.

Application

• Biomedical Research: Used as a critical reference standard in studies investigating the role of cysteinyl leukotrienes in asthma, allergic rhinitis, and other inflammatory conditions.
• Pharmaceutical Development: Serves as a key analytical standard in the discovery and validation of leukotriene receptor antagonists and synthesis pathway inhibitors.
• Diagnostic Assay Calibration: Employed as a calibrant or control in the development of immunoassays (e.g., ELISA) for quantifying leukotriene levels in biological samples.
• Metabolic Pathway Analysis: Essential for in vitro and in vivo studies mapping the arachidonic acid cascade and eicosanoid biosynthesis pathways.
• Academic & Institutional Research: A fundamental tool for university and government laboratories studying cellular signaling, receptor pharmacology, and mediator biology.
• Quality Control: Used as a system suitability standard in analytical methods (HPLC, LC-MS) to ensure accuracy and precision in related pharmaceutical quality control labs.

Basic Information

Product Name	Leukotriene D5
CAS No.	79695-13-9
Molecular Formula	C₃₀H₄₇NO₇S
Molecular Weight	565.8 g/mol
Synonyms	LTD5; (5S,6R)-6-[(1E,3E,5Z,8Z)-Tetradeca-1,3,5,8-tetraen-1-yl]-2-azaspiro[4.5]decane-1,4-dione (incorrect but related); 5(S)-Hydroxy-6(R)-S-cysteinyl-7,9,11,14-eicosatetraenoic Acid (variant); Cysteinyl Leukotriene D5; 5S-Hydroxy-6R-cysteinyl-7E,9E,11Z,14Z-eicosatetraenoic Acid; Leukotriene D5 (LTD5); (5S,6R)-LTD5; 5(S)-Hydroxy-6(R)-S-glutathionyl-7,9,11,14-eicosatetraenoic Acid metabolite.
EINECS	Contact for details

Quality Control

Our Leukotriene D5 is manufactured under strict quality systems to ensure the highest standards of purity and consistency for research applications. Each batch is thoroughly characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is easily oxidized and light-sensitive; allow it to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.