Description

Brimonidine Tartrate is a highly selective α-2 adrenergic receptor agonist, widely recognized for its potent pharmacological activity. This compound is of critical importance in the pharmaceutical industry for its primary role in lowering intraocular pressure. It is an essential active pharmaceutical ingredient (API) for manufacturers developing ophthalmic solutions and other advanced therapeutic formulations. Global suppliers and pharmaceutical companies rely on a consistent, high-purity supply of Brimonidine Tartrate CAS NO 79570-19-7 for production.

Application

• Ophthalmic Solutions: Primary API in prescription eye drops for the treatment of open-angle glaucoma and ocular hypertension.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex adrenergic compounds.
• Research & Development: Used in preclinical and clinical studies targeting α-2 adrenergic pathways.
• Generic Drug Manufacturing: Critical for producing cost-effective generic versions of branded glaucoma medications.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for ocular conditions in animals.
• Controlled-Release Formulations: Incorporated into advanced drug delivery systems for sustained therapeutic effect.

Basic Information

Item	Detail
Product Name	Brimonidine Tartrate
CAS No.	79570-19-7
Molecular Formula	C11H10BrN5 • C4H6O6
Molecular Weight	442.24 g/mol (for tartrate salt)
Synonyms	5-Bromo-6-(2-imidazolidinylideneamino)quinoxaline L-tartrate; UK-14,304-18; Brimonidine L-tartrate; AGN 190342; Alphagan® (brand name API); AGN-190342; Brimonidine (base); UK 14,304-18
EINECS	Contact for details

Quality Control

Our Brimonidine Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical standards, including potential compliance with USP/EP monographs. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.